View source for 1dj7

[[Image:1dj7.gif|left|200px]]<br /><applet load="1dj7" size="350" color="white" frame="true" align="right" spinBox="true" 
caption="1dj7, resolution 1.6&Aring;" />
'''CRYSTAL STRUCTURE OF FERREDOXIN THIOREDOXIN REDUCTASE'''<br />

==Overview==
Light generates reducing equivalents in chloroplasts that are used not only for carbon reduction, but also for the regulation of the activity of chloroplast enzymes by reduction of regulatory disulfides via the ferredoxin:thioredoxin reductase (FTR) system. FTR, the key electron/thiol transducer enzyme in this pathway, is unique in that it can reduce disulfides by an iron-sulfur cluster, a property that is explained by the tight contact of its active-site disulfide and the iron-sulfur center. The thin, flat FTR molecule makes the two-electron reduction possible by forming on one side a mixed disulfide with thioredoxin and by providing on the opposite side access to ferredoxin for delivering electrons.

==About this Structure==
1DJ7 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Synechocystis_sp. Synechocystis sp.] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=SF4:'>SF4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJ7 OCA]. 

==Reference==
Redox signaling in chloroplasts: cleavage of disulfides by an iron-sulfur cluster., Dai S, Schwendtmayer C, Schurmann P, Ramaswamy S, Eklund H, Science. 2000 Jan 28;287(5453):655-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10649999 10649999]
[[Category: Protein complex]]
[[Category: Synechocystis sp.]]
[[Category: Dai, S.]]
[[Category: Eklund, H.]]
[[Category: Ramaswamy, S.]]
[[Category: Schurmann, P.]]
[[Category: Schwendtmayer, C.]]
[[Category: SF4]]
[[Category: SO4]]
[[Category: 4fe-4s cluster binding fold with cxcx16cxcx8cxc binding motif]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:17:06 2008''