View source for 6y5r


==Structure of Human Potassium Chloride Transporter KCC3 S45D/T940D/T997D in NaCl==
<StructureSection load='6y5r' size='340' side='right'caption='[[6y5r]], [[Resolution|resolution]] 3.76&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6y5r]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y5R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Y5R FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6y5r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y5r OCA], [http://pdbe.org/6y5r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6y5r RCSB], [http://www.ebi.ac.uk/pdbsum/6y5r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6y5r ProSAT]</span></td></tr>
</table>
== Disease ==
[[http://www.uniprot.org/uniprot/S12A6_HUMAN S12A6_HUMAN]] Corpus callosum agenesis-neuronopathy syndrome. The disease is caused by mutations affecting the gene represented in this entry. 
== Function ==
[[http://www.uniprot.org/uniprot/S12A6_HUMAN S12A6_HUMAN]] Mediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells. 
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Abrusci, P]]
[[Category: Arrowsmith, C H]]
[[Category: Bohstedt, T]]
[[Category: Bountra, C]]
[[Category: Burgess-Brown, N A]]
[[Category: Chalk, R]]
[[Category: Chi, G]]
[[Category: DiMaio, F]]
[[Category: Duerr, K L]]
[[Category: Ebenhoch, R]]
[[Category: Edwards, A M]]
[[Category: MacLean, B]]
[[Category: Man, H]]
[[Category: Marsden, B D]]
[[Category: McKinley, G]]
[[Category: Moreau, C]]
[[Category: Mukhopadhyay, S M.M]]
[[Category: Pike, A C.W]]
[[Category: Reggiano, G]]
[[Category: Structural genomic]]
[[Category: Singh, N K]]
[[Category: Snee, M]]
[[Category: Wang, D]]
[[Category: Apc]]
[[Category: Dimer]]
[[Category: Kcc3]]
[[Category: Membrane protein]]
[[Category: Potassium chloride]]
[[Category: PSI, Protein structure initiative]]
[[Category: Sgc]]
[[Category: Slc12a6]]
[[Category: Transporter]]