6y5r

Structure of Human Potassium Chloride Transporter KCC3 S45D/T940D/T997D in NaClStructure of Human Potassium Chloride Transporter KCC3 S45D/T940D/T997D in NaCl

Structural highlights

6y5r is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

[S12A6_HUMAN] Corpus callosum agenesis-neuronopathy syndrome. The disease is caused by mutations affecting the gene represented in this entry.

Function

[S12A6_HUMAN] Mediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells.

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OCA