View source for 5svc


==Mechanism of ATP-Dependent Acetone Carboxylation, Acetone Carboxylase nucleotide-free structure==
<StructureSection load='5svc' size='340' side='right'caption='[[5svc]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5svc]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Xanthobacter_autotrophicus_Py2 Xanthobacter autotrophicus Py2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SVC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SVC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5svc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5svc OCA], [https://pdbe.org/5svc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5svc RCSB], [https://www.ebi.ac.uk/pdbsum/5svc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5svc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACXA_XANP2 ACXA_XANP2] Catalyzes the carboxylation of acetone to form acetoacetate. Has a reduced activity on butanone, and no activity on 2-pentatone, 3-pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide.<ref>PMID:9237998</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Xanthobacter autotrophicus Py2]]
[[Category: Alleman AB]]
[[Category: Dubois JL]]
[[Category: Eilers BJ]]
[[Category: Kabasakal BV]]
[[Category: Murray JW]]
[[Category: Mus F]]
[[Category: Nocek BP]]
[[Category: Peters JW]]