Vacuolar protein sorting-associated protein 3D structures

3D structures of vacuolar protein sorting-associated protein3D structures of vacuolar protein sorting-associated protein

Updated on 17-March-2024- For a general description of the protein see Vacuolar protein sorting-associated protein

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• Vps4 domains: MIT 1-82; AAA ATPase 124-437
  • 5xmi – yVps4 + ATP – yeast - Cryo EM
    
  • 2rko – yVps4 AAA ATPase domain
    
  • 3eie – yVps4 AAA ATPase domain (mutant)
    
  • 3eih – yVps4 AAA ATPase domain (mutant) + ATPγS
    
  • 2qp9 – yVps4 83-437
    
  • 2qpa – yVps4 (mutant) 83-437 + ADP
    
  • 2v6x – yVps4 MIT domain + yVps2 C-terminal
    
  • 4niq, 5fvk – yVps4 MIT domain + yVfa1 MIM2 domain
    
  • 5fvl – yVps4 MIT domain + yVPS20
    
  • 3mhv – yVps4 + yVps Vta1
    
  • 6ap1 – yVps4 + yVps Vta1 + peptide
    
  • 6oo2, 6ndy – yVps4 + yVps Vta1 + peptide - Cryo EM
    
  • 5uie – yVps4 + yVps2 + yVps Vta1 – Cryo EM
    
  • 5xmk – yVps4 (mutant) + yVps Vta1 + ATP – Cryo EM
    
  • 6bmf – yVps4 AAA ATPase domain + yVps2P – Cryo EM
    
• CHMP1B
  • 6tz9 – hCHMP1B – human – Cryo EM
    
• Vps2-1 or CHMP2A
  • 7zcg, 7zch – hVps2-1 + hVsp24 – Cryo EM
    
• Vps4A
  • 1yxr – hVps4A MIT domain – human - NMR
    
  • 2jq9 – hVps4A MIT domain + CHMP1A peptide - NMR
    
  • 2k3w – yVps4A MIT domain + CHMP6 peptide - NMR
    
• Vps4B or Skd1
  • 2jqh, 2cpt, 1wr0 – hVps4B MIT domain - NMR
    
  • 1xwi – hVps4B C-terminal
    
  • 4u7y – hVps4B MIT domain + IST1 peptide
    
  • 2jqk – hVps4B MIT domain + CHMP2B
    
  • 7l9x – hVps4B + inhibitor
    
  • 2zam – mVps4B - mouse
    
  • 2zao – mVps4B + ADP
    
  • 2zan – mVps4B + ATP
    
• Vps4P
  • 6ap1 – yVps4P + Vta1 + peptide + ADP - Cryo EM
    
• Vps5
  • 6h7w – CtVps5 in retromer – Chaetomium thermophilum - Cryo EM
    
• Vps9
  • 1mn3 – yVps9 CUE domain 398-451
    
  • 1p3q – yVps9 CUE domain + ubiquitin
    
• Vps9A
  • 4g01 – Vps9A + RABF2B – Arabidopsis thaliana
    
• Vps11
  • 7zu0 – hVps11 + Vps16 + Vps18 + Vps33 + Vps39 + Vps41 in HOPS tethering complex – Cryo EM
    
  • 8cuk – yVps11 WD40 domain 1-350
    
• Vps13
  • 6cbc – CtVps13 N-terminal (mutant)
    
• Vps15 or serine/threonine protein kinase Vps15
  • 3gre – yVps15 WD repeat domain
    
• Vps17
  • 7x4o – yVps17
    
• Vps18
  • 4uuy – yVps18
    
• Vps23
  • 2f6m – yVps23 C-terminal (mutant) + yVps28 N-terminal
    
  • 3r42 – yVps23 N-terminal (mutant) + yVps27 peptide
    
  • 2caz – yVps23 + yVps28 N-terminal + SRN2
    
  • 2f66 – yVps23 C-terminal + yVps28 N-terminal + SRN2
    
  • 2p22 – yVps23 + yVps28 N-terminal + SRN2 + peptide
    
  • 1uzx – yVps23 UEV domain 1-161 + ubiquitin
    
  • 3r3q – yVps23 UEV domain
    
• Vps24 or CHMP3
  • [[[2gd5]], [3frt]], 3frv – hVps24
    
  • 6zh3 – yVps24 - Cryo EM
    
• Vps25
  • 3htu – hVps23 C-terminal WH2 domain + hVps20 first helix
    
• Vps 26
  • 2fau – hVps26
    
• Vps 26A
  • 7blo – hVps26A + hVps35 + nexin-3 + DMT1 peptide - Cryo EM
    
  • 4p2a – mVps26A + sorting nexin-3
    
  • 6vac – mVps26A + Vps29 + Vps35
    
  • 7u6f – mVps26A + Vps29 + Vps35 – Cryo EM
    
  • 6md5 – Vps26A – zebrafish
    
  • 7blq – CtVps26 + Vps35 + nexin-3 +Kex2 – Chaetomium thermophilum – Cryo EM
    
  • 5f0l, 5f0m, 5f0p – Vps26A + Vps35 + SNX3
    
• Vps26B
  • 3lh8, 2r51 – mVps26B
    
  • 3lh9, 3lha – mVps26B (mutant)
    
• Vps26C
  • 8syn, 8syo – hVps26C + Vps29 + Vps35L – Cryo EM
    
• Vps26-like
  • 6h7w – CtVps26L + Vsp29 + Vsp35 - Cryo EM
    
• Vps27
  • 2pjw – yVps27 C-terminal + protein
    
  • 6njg – yVps27 + polyubiquitin
    
• Vps28
  • 6vme – hVps28 in ESCRT-I complex
    
  • 2g3k, 2j9v – yVps28 C-terminal
    
  • 2j9u – yVps28 + yVps36
    
• Vps29
  • 7bln, 8sym – hVps29 + hVps35 - Cryo EM
    
  • 8ese – hVps29 + hVps35 peptide
    
  • 5wyh – hVps29 + interaptin
    
  • 5osh, 5osi – hVps29 + hVps35 + interaptin
    
  • 5gtu – hVps29 + TBC1D5
    
  • 3psn, 3pso – mVps29
    
  • 6vab – mVps29 + Vps35 – Cryo EM
    
  • 6tl0 – mVps29 + VARP – NMR
    
  • 2r17 – yVps29 + yVps35
    
  • 5w8m – CtVps29
    
  • 6xs5, 6xs7, 6xs8, 6xs9, 6xsa – CtVps29 + peptide
    
  • 6h7w – CtVps29 + CtVps35 + CtVps26-like + CtVPS - Cryo EM
    
  • 7blp, 7blr – CtVps29 + CtVps35 - Cryo EM
    
  • 5xce, 5xch – EhVps29 – Entamoeba histolytica
    
  • 5xcj, 5xck – EhVps29 (mutant)
    
• Vps30
  • 3vp7 – hVps30 C-terminal
    
• Vps32 or Snf7 or CHMP5
  • 4abm – hVps32-2 hairpin 23-97
    
  • 5fd9 – hVps32
    
  • 3uly, 3um0, 3um1, 3um2, 3um3 – hVps32-2 C terminal + BROX
    
  • 5fd7, 5t8l, 5t8n – yVps32
    
• Vps33
  • 5bv1 – CtVps33 + CtVps16
    
  • 5bv0 – CtVps33 + CtVps16 + NYV1 + SM protein
    
  • 8dit – CtVps33 + CtVps16 + CtVsp18 – Cryo EM
    
• Vps33A
  • 4bx8 – hVps33A
    
  • 4bx9 – hVps33A + hVps16 C-terminal + SNARE domain
    
• Vps34
  • 5dfz – yVps34 + yVps38 + yVps15 + yVps30 + nanobody
    
• Vps35
  • 5f0k – hVps35 N-terminal
    
  • 5f0j – hVps35 + hVps26A + sorting nexin-3
    
  • 5f0l, 5f0m, 5f0p – hVps35 + hVps26A + sorting nexin-3 + DMT-1
    
  • 6vac – mVps35 + mVps26A + mVps29 - Cryo EM
    
• Vps36
  • 5kc2 – yVps36 + yVps15
    
  • 2hth – hVps36 GLUE domain 1-138 + ubiquitin
    
  • 2zme, 3cuq – hVps36 + hVps25 + SNF8
    
• Vps37A
  • 8e22 – hVps37A
    
• Vps45
  • 6xjl – CtVps45
    
  • 6xmd, 6xm1 – CtVps45 + Tig2 Qa SNARE
    
• Vps46
  • 3ggz – yVps46 MIM motif 176-204 + IST1
    
• Vps53
  • 3ns4 – yVps53 C-terminal
    
• Vps54
  • 3n1b – yVps54 C-terminal
    
  • 3n1e – mVps54 C-terminal
    
• Vps60
  • 2luh – yVps60 + yVps Vta1 - NMR
    
• Vps64
  • 6a8w – yVps64 FHA domain
    
• Vps72
  • 6gej, 6gen – yVps72 in nucleosome – Cryo EM
    
• Vps72 homolog
  • 5chl – Vps72 + histone H2A.Z – Drosophila melanogaster
    
  • 5fug – hVps72 N-terminal + histone H2A.Z
    
• Vps74
  • 2zih, 2zii – yVps74
    
  • 4tu3 – yVps74 + SAC1
    
• Vps75
  • 3c9b, 3c9d, 5agc – yVps75
    
  • 3dm7 – yVps75 (mutant)
    
  • 2zd7 – yVps75 + peptide
    
  • 3q68, 3q66 – yVps75 + histone acetyltransferase
    
  • 3q33 – yVps75 + histone acetyltransferase + histone H3 peptide
    
  • 6o22 – yVps75 + histone acetyltransferase + histone H3 peptide + histone H4 peptide + ASF1 - NMR
    
  • 3q35 – yVps75 + histone acetyltransferase + acetyl CoA
    
  • 5yps – Vps75 (mutant) – Pneumocystis carinii
    
• Vps Vta1 or Lip5
  • 2lxl – hVps Vta1
    
  • 4txp – hVps Vta1 N-terminal
    
  • 2rkk – yVps Vta1 N-terminal
    
  • 2rkl – yVps Vta1 C-terminal
    
  • 5h7p – yVps Vta1 N-terminal + yVps46 D1-D2 domain - NMR
    
  • 4u7e – hVps Vta1 N-terminal + IST1
    
  • 2lxm – hVps Vta1 N-terminal + CHMP5
    
  • 4txq – hVps Vta1 N-terminal + CHMP1B
    
  • 4txr – hVps Vta1 N-terminal + CHMP1B + CHMP5