User:Andrew Peters/Sandbox 1

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ALK H. sapiensALK H. sapiens

Introduction

Figure 1

Function

Conformation Change

Disease

NSCLC

enter [1]

Cancer

[2]

Relevance

[2]

Structural highlights

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.


ALK 7LS0

Drag the structure with the mouse to rotate

ReferencesReferences

  1. Du X, Shao Y, Qin HF, Tai YH, Gao HJ. ALK-rearrangement in non-small-cell lung cancer (NSCLC). Thorac Cancer. 2018 Apr;9(4):423-430. doi: 10.1111/1759-7714.12613. Epub 2018 Feb, 28. PMID:29488330 doi:http://dx.doi.org/10.1111/1759-7714.12613
  2. 2.0 2.1 Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677

Student ContributorsStudent Contributors

  • Drew Peters