Ribosomal protein S1
Ribosomal protein S1 (RPS1) is one of the 21 proteins which belong to the 30S small subunit of the bacterial ribosome or the 30 proteins which belong to the 40S small subunit of the eukaryotic ribosome. It participates in translation initiation of many mRNAs and plays a role in translation elongation[1]. It consists of 6 repeats of 70-residue domains able to bind single-stranded nucleic acids named OB folds.
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3D Structures of Ribosomal protein S13D Structures of Ribosomal protein S1
Updated on 02-March-2022
4v88 – RPS1 in 40S subunit + suppressor protein STM1 + RACK1 – yeast
2mfi - EcRPS1 domain 1 11-100 - NMR – Escherichia coli
2mfl - EcRPS1 domain 1-2 1-179 - NMR
4q7j, 4r71 - EcRPS1 domain 1-3 1-273 + elongation factor Tu + elongation factor Ts + beta helicase
2khi – EcRPS1 domain 4 267-361 - NMR
5xq5 – EcRPS1 domain 5 350-443 – NMR
2khj - EcRPS1 domain 6 441-528 - NMR
1sro - EcRPS1 RNA binding domain 617-692 – NMR
4toi – EcRPS2 1-236/RPS1 3-84
4nng - MtRPS1 pyranozoic acid binding domain residues 285-435 (mutant) – Mycobacterium tuberculosis
4nnh, 4nnk - MtRPS1 pyranozoic acid binding domain
4nni - MtRPS1 pyranozoic acid binding domain + pyranozoic acid
5ie8 - RPS1 pyranozoic acid binding domain - Mycobacterium leprae - NMR
7a05 - RPS1 domain 3-4 – Vibrio vulnificus - NMR
ReferencesReferences
- ↑ Qu X, Lancaster L, Noller HF, Bustamante C, Tinoco I Jr. Ribosomal protein S1 unwinds double-stranded RNA in multiple steps. Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14458-63. doi:, 10.1073/pnas.1208950109. Epub 2012 Aug 20. PMID:22908248 doi:http://dx.doi.org/10.1073/pnas.1208950109