Ribosomal protein L4

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Ribosomal protein L4 (RPL4 )[1] is one of the 34 proteins which belong to the of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome. It may actively participate in the catalysis of peptide bond formation[2].. In the archaea like in Haloarcula marismortui the L4 is called L4P (RPL4P).

Ribosomal protein L4 complex with citric acid (PDB code 1dmg)

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3D Structures of Ribosomal protein L43D Structures of Ribosomal protein L4

Updated on 27/02/2022

RPL4RPL4

1dmg – RPL4 – Thermotoga maritima
1j5a, 1jzx, 1jzy, 1jzz, 1k01 – RPL4 + RPL22 + RPL32 + 23S RRNA + antibiotic – Deinococcus radiodurans
5tqb – RPL4 + ACL4 – Chaetonium thermophilum

ReferencesReferences

  1. Worbs M, Huber R, Wahl MC. Crystal structure of ribosomal protein L4 shows RNA-binding sites for ribosome incorporation and feedback control of the S10 operon. EMBO J. 2000 Mar 1;19(5):807-18. PMID:10698923 doi:http://dx.doi.org/10.1093/emboj/19.5.807
  2. Yates JL, Nomura M. E. coli ribosomal protein L4 is a feedback regulatory protein. Cell. 1980 Sep;21(2):517-22. PMID:6996835

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