Protein disulfide oxidoreductase

Function Protein disulfide oxidoreductase (PDOR) catalyzes disulfide bond formation in proteins and is critically important in protein folding. In bacteria PDOR are known as DsbA and DsbB. PDOR catalyze dithiol-disulfide exchange reactions, i.e., conversion of RSSR and R’SH to R’SSR’ and RSH. Structural highlights PDOR DsnA contains the in the active site. The 2 cysteines can undergo reversible oxidation-reduction in the catalytic process. 3D structures of protein disulfide oxidoreductase Protein disulfide oxidoreductase 3D structures For DsbB see Thiol:disulfide interchange protein.

spinqualitylabelsall models DsbA (PDB entry 3bci) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image