Prion 3D structures

3D structures of prion3D structures of prion

Updated on 12-September-2023

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• Prion short polypeptides
  • 3nvf – hPrP residues 138-143 – human
    
  • 6pq5 - hPrP residues 113-118
    
  • 6pqa - hPrP residues 119-124
    
  • 2ol9 - hPrP residues 170 – 175
    
  • 3nhc, 3nhd, 3md4, 3md5 - hPrP residues 127 – 132
    
  • 2iv5 - hPrP residues 173 -195 – NMR
    
  • 1oei - hPrP residues 61 - 84 – NMR
    
  • 1oeh - hPrP residues 61 - 68 – NMR
    
  • 2lbg - hPrP residues 110 - 136 – NMR
    
  • 2iv6 - hPrP residues 173-195 (mutant) – NMR
    
  • 2iv4 - hPrP residues 180-195 – NMR
    
  • 4e1h, 4e1i - hPrP residues 177 -182 + 211-216
    
  • 1skh - bPrP residues 1 – 30 - bovine
    
  • 3fva - ePrP residues 173-178 – Elk
    
  • 1s4t - sPrP residues 135 – 155 – sheep – NMR
    
  • 1m25 - sPrP residues 152 – 156 – NMR
    
  • 1g04 - sPrP residues 145 – 169 – NMR
    
  • 2rmv, 2rmw - sPrP residues 142 – 166 (mutant) – NMR
    
  • 6axz, 6btk - vPrP residues 168 - 176 – vole
    
  • 3nve – ShPrP residues 138 -143 – Syrian hamster
    
  • 2kkg - GhPrP residues 23 -106 – Golden hamster - NMR
    
  • 7yat - GhPrP residues 108-144 – Cryo EM
    
  • 3nvg, 3nvh - mPrP residues 138 -143 – mouse
    
• Prion
  • 6lni - hPrP residues 23-231 – Cryo EM
    
  • 7dwv - hPrP residues 23 -231 (mutant) – Cryo EM
    
  • 7fhq - hPrP residues 91 -231 (mutant) – Cryo EM
    
  • 6uur - hPrP residues 94 -178 (mutant) – Cryo EM
    
  • 7rl4 - hPrP residues 23-144 – Cryo EM
    
  • 7umq, 7un5 - hPrP residues 80-141 – Cryo EM
    
  • 3haf, 3hak, 3hj5, 1i4m - hPrP C-terminal 125-277
    
  • 1hjm, 1hjn, 2kun, 5l6r, 5yj5 – hPrP C-terminal – NMR
    
  • 1h0l, 1fkc, 2k1d, 1fo7, 1e1s, 1e1g, 1e1j, 1e1p, 1e1u, 1e1w, 1qlx, 1qlz, 1qm0, 1qm1, 1qm2, 1qm3, 1qlz, 1qm0, 1qm1, 2lej, 5yj4 - hPrP C-terminal (mutant) - NMR
    
  • 3heq, 3her, 3hes, 3hjx - hPrP C-terminal (mutant)
    
  • 6du9 - hPrP residues 90 -231
    
  • 2lft, 2lsb, 2m8t - hPrP residues 90 -231 – NMR
    
  • 2lv1 - hPrP residues 90 -231 (mutant) – NMR
    
  • 2lsb - hPrP residues 120 -230 + antibody
    
  • 3o79 – rPrP C-terminal – rabbit
    
  • 4hls, 4hmm, 4hmr- rPrP C-terminal (mutant)
    
  • 2fj3 - rPrP C-terminal – NMR
    
  • 2joh, 2jom - rPrP C-terminal (mutant) – NMR
    
  • 1xyw, 3fva – ePrP C terminal - NMR
    
  • 2ku4 - PrP C-terminal – horse
    
  • 2kfl - PrP C-terminal – Wallaby – NMR
    
  • 2ktm – sPrP residues 167-234 H2H3 domain (mutant) – NMR
    
  • 1xyu, 1y2s, 2n53 - sPrP C-terminal – NMR
    
  • 2mv8, 2mv9 - sPrP C-terminal (mutant) – NMR
    
  • 1uw3 - sPrP C-terminal
    
  • 6fnv - mdPrP residues 94-233 – mule deer
    
  • 1u3m – PrP C-terminal – chicken – NMR
    
  • 1u5l - PrP C-terminal – turtle – NMR
    
  • 1xu0 - PrP C-terminal – frog – NMR
    
  • 1xyj - PrP C-terminal – cat – NMR
    
  • 1xyk - PrP C-terminal – dog – NMR
    
  • 1xyq - PrP C-terminal – pig – NMR
    
  • 1dwy, 1dx0, 1dx1 - bPrP C-terminal – NMR
    
  • 1dwz - bPrP C-terminal (mutant) - NMR
    
  • 1b10 - ShPrP C-terminal – NMR
    
  • 2lh8 - ShPrP C-terminal + thiamine – NMR
    
  • 7lna - GhPrP – Cryo EM
    
  • 2k56 - PrP C-terminal – Vole – NMR
    
  • 2ku5, 2ku6, 2kfm, 2kfo, 2k5o, 1y16, 1y15 - mPrP C-terminal (mutant) - NMR
    
  • 8efu - mPrP – Cryo EM
    
  • 8dja - mPrP residues 23-143 – Cryo EM
    
  • 7qig, 7td6, 8a00 - mPrP residues 94-229 – Cryo EM
    
  • 1xyx - mPrP C-terminal - NMR
    
  • 2l1k, 2l1d, 2l1e, 2l40 - mPrP C terminal (mutant) – NMR
    
• Yeast prions
  • 2onx, 2olx – Sup35 residues 8 - 11 – yeast
    
  • 2omm, 1yjo, 1yjp – Sup35 residues 7 – 13
    
  • 1jzr, 1k0a, 1k0b, 1k0c, 1k0d – Ure2p + glutathione derivartive
    
  • 1g6w, 1g6y – Ure2p globular domain
    
  • 1hqo – Ure2p nitrogen regulation fragment
• Prion complex with antibody
  • 2w9e, 4h88, 2lsb, 4dgi, 6aq7 - hPrP C-terminal + anti-PrP antibody
    
  • 4n9o - hPrP C terminal + nanobody
    
  • 4kml - hPrP residues 24-231 + nanobody
    
  • 6suz, 6sv2 - hPrP residues 125 - 223 + antibody
    
  • 2hh0 - bPrP peptide epitope + anti-PrP antibody
    
  • 4yx2 - bPrP + antibody
    
  • 1tpx, 1tqb, 1tqc - sPrP C-terminal + anti-PrP antibody
    
  • 4yxh - mdPrP + antibody
    
  • 4yxk - ePrP + antibody
    
  • 4yxl - GhPrP + antibody
    
  • 4j8r - mPrP residues 67-82 + antibody
    
  • 4ma7, 4ma8 - mPrP residues 116 - 229 + antibody
    
  • 6her, 6hhd - mPrP residues 117 - 226 + nanobody
    
  • 1cu4 - ShPrP peptide epitope + anti-PrP antibody
    
• HET-S from Podospora anserine
  • 2kj3, 2rnm – HET-S C-terminal – NMR
    
  • 2wvn, 2wvo - HET-S N-terminal
    
  • 2wvq - HET-S N-terminal (mutant)