Ketol-acid reductoisomerase

Function Ketol-acid reductoisomerase (KARI) is a bifunctional enzyme which catalizes two steps in the biosynthesis of branched-chain amino acids. KARI catalyzes the isomerization of alkyls and the NADPH-dependent reduction of a 2-ketoacid. There are two forms of KARI. A short form – Class I – found in fungi and most bacteria and a long form. For the active site see Arnold lab: coenzyme specificity – Class II – found in plants. 3D Structures of Ketol-acid reductoisomerase Ketol-acid reductoisomerase 3D structures

spinqualitylabelsall models E. coli class II ketol-acid reductoisomerase complex with NADPH, sulfate and Mg+2 ion (PDB code 3ulk) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image