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<StructureSection load='1AVD' size='300' side='left' caption='Crystal Structure of Avidin With Biotin (PDB code 1avd)'>

Avidin is a protein that’s bind Vitamin B7, . The Avidin is produced in the ovary of some lay eggs animals, and it’s found in the white of the egg [1].

StructureStructure

Avidin is a tetrameric protein, but here will be shown only two units of the whole structure just to simplify it.

The secondary structure of each Avidin monomer combines (pink) and an 8 stranded antiparalle (turquoise). The tertiary structure of each monomer is beta-barrel [2].

Structural highlightsStructural highlights

Because of the curved structure of the protein, it’s easier to see where the N terminus is begins and the C terminus ends with .

 Amino Terminus                 Carboxy Terminus 

ReferencesReferences

  1. Green NM. Avidin. Adv Protein Chem. 1975;29:85-133. doi: 10.1016/s0065-3233(08)60411-8. PMID:237414 doi:http://dx.doi.org/10.1016/s0065-3233(08)60411-8
  2. Livnah O, Bayer EA, Wilchek M, Sussman JL. Three-dimensional structures of avidin and the avidin-biotin complex. Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5076-80. PMID:8506353

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Hila Cohen, Michal Harel