GTPase Hras 3D structures

3D structures of GTPase Hras3D structures of GTPase Hras

Updated on 24-April-2023

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• HRAS p21 catalytic domain residues 1-166
  • 5p21, 221p, 1ioz, 1p2t, 3k8y, 3l8z, 3rry, 3tgp, 3lbh, 4dlr, 4dls, 4dlt, 4dlu, 4dlv, 4dlw, 4dlx, 4dly, 4dlz - hHRAS – human
    
  • 1plj, 1plk, 1pll – hHRAS - Laue
    
  • 221p, 421p, 521p, 621p, 721p, 821p, 1agp, 3i3s, 3k9n, 3lo5, 3k9l, 3oiu, 3oiv, 3oiw – hHRAS (mutant)
    
  • 2n42, 2n46 - hHRAS (mutant) – NMR
    
  • 3v4f – HRAS - rat
• HRAS p21 catalytic domain complex with nucleotides
  • 1q21, 4q21 – hHRAS + GDP
    
  • 1crp, 1crq, 1crr, 1aa9 – hHRAS + GDP - NMR
    
  • 4l9s, 6dzh, 6mqt, 1lf0, 1zw6, 2cl6, 2cl7, 2clc, 2cld, 2ce2, 2quz, 2x1v, 2q21, 7jii, 7tam 2evw, 1jah, 1jai - hHRAS (mutant) + GDP
    
  • 5vbe, 5vbz - hHRAS (mutant) + GDP + pyrazole derivative
    
  • 7oga, 7ogb, 7ogc - hHRAS + GNP
    
  • 7jif, 7jig, 7jih, 7ogd, 7oge, 7ogf - hHRAS (mutant) + GNP
    
  • 5zc6 - hHRAS (mutant) + GNP + naphthalene derivative
    
  • 5wdo - hHRAS + GMPPNP
    
  • 4l9w, 5wdp, 5wdq - hHRAS (mutant) + GMPPNP
    
  • 6q21, 121p – hHRAS + GCP
    
  • 1qra - hHRAS + GTP
    
  • 1lf0, 1zw6, 2cl6, 2cl7, 2clc, 2evw, 1jah, 1jai- hHRAS (mutant) + GTP
    
  • 1clu, 1rvd, 1iaq, 1gnr - hHRAS (mutant) + GTP derivative
    
  • 1ctq, 4efl, 4rsg, 5b2z, 5b30, 5x9s - hHRAS + GPPNHP
    
  • 1xcm, 2cl0, 2rga, 2rgb, 2rgc, 2rgd, 2rge, 2rgg, 3kkm, 3kkn, 4efm, 4efn, 6e6c, 6e6p, 7dph, 7dpj - hHRAS (mutant) + GPPNHP
    
  • 1gnp, 1gnq, 6q21 - hHRAS + guanylate derivative
    
  • 4xvq, 4xvr - hHRAS (mutant) + guanylate derivative
    
  • 2lcf - hHRAS (mutant) + guanylate derivative - NMR
    
  • 1p2s, 1p2u, 1p2v, 3rrz, 3rs0, 3rs2, 3rs4, 3rs7, 3rsl, 3rso - hHRAS + alcohol + guanylate derivative
    
  • 3rs3, 3rs5 - hHRAS + small organic molecule + guanylate derivative
    
  • 3lbh, 3lbi, 3lbn - hHRAS + salt + guanylate derivative
    
  • 3l8y - hHRAS + cyclen + guanylate derivative
    
  • 6zl3 – hHRAS + inhibitor + GDP
    
  • 6zj0 – hHRAS + inhibitor + GCP
    
  • 2lwi – hHRAS (mutant) + inhibitor + GNP
    
• HRAS p21 catalytic domain complex with protein
  • 1wq1 - hHRAS + p120GAP catalytic domain
    
  • 1bkd, 1nvw - hHRAS + son of sevenless-1
    
  • 5wfo, 5wfp, 5wfq, 5wfr - hHRAS + son of sevenless-1 homolog
    
  • 1nvu, 1nvv, 1nvx, 1xd2, 4nyi, 4nyj, 4nym - hHRAS (mutant) + son of sevenless-1 homolog
    
  • 4uru, 4urv, 4urw, 4urx, 4ury, 4urz, 4us0, 4us1, 4us2 - hHRAS + son of sevenless-1 + inhibitor
    
  • 6bvj, 6bvk - hHRAS + son of sevenless-1 + activator
    
  • 6bvi, 6bvl, 6bvm, 6cuo, 6cup, 6cur, 6d55, 6d56, 6d59, 6d5e, 6d5g, 6d5h, 6d5j, 6d5l, 6d5m, 6d5v, 6d5w - hHRAS (mutant) + son of sevenless-1 + activator
    
  • 1k8r - hHRAS + Byr2 RAS-binding domain
    
  • 2c5l - hHRAS (mutant) + phosphoinositide-specific phospholipase RA2 domain
    
  • 2uzi, 2vh5 - hHRAS (mutant) + antibody
    
  • 3ddc - hHRAS (mutant) + Ras association domain containing family protein RAS-binding domain
    
  • 3kud - hHRAS + RAF proto-oncogene Ser/Thr-protein kinase + GDP
    
  • 4g0n, 7jhp - hHRAS + RAF proto-oncogene Ser/Thr-protein kinase + GNP
    
  • 6ntc, 4g3x, 6ntd - hHRAS (mutant) + RAF proto-oncogene Ser/Thr-protein kinase + GNP
    
  • 1lfd - hHRAS + Ral guanine nucleotide dissociation stimulator RAS-binding domain
    
  • 4k81 – hHRAS + growth factor receptor-bound protein
    
  • 5e95 – hHRAS + MB(NS1)
    
  • 6axg – hHRAS + Ras guanyl-releasing protein 1
    
  • 5wpl – hHRAS + Ras-binding peptide
    
  • 6amb – hHRAS + afadin
    
  • 1he8 – hHRAS (mutant) + P3K
    
  • 6kyh – hHRAS + Shank3 + GNP
    
  • 7vv8, 7vv9, 7vvg – hHRAS + TORC2 + GNP
    
  • 7l0f, 7l0g – hHRAS + monobody + GSP