Diacylglycerol kinase

Function Diacylglycerol kinase (DAGK) catalyzes the conversion of diacylglycerol to phosphaditic acid using ATP as energy source. DAGK is active upon receptor activation of the phosphoinositide pathway. The bacterial DAGK contains 2 families: DgkA and DgkB. Relevance DAGK is tested as a possible therapeutic target for neuronal diseases. Structural highlights In DAGK DgkB the is found at the interface between the 2 domains of the structure. Water molrcules are shown asred spheres. 3D Structures of diacylglycerol kinase Diacylglycerol kinase 3D structures

spinqualitylabelsall models Diacylglycerol kinase DkgB complex with ADP and Mg+2 ion (green) (PDB code 2qv7) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image