CAMP-dependent pathway

The cAMP-dependent pathway, also known as the adenylyl cyclase pathway, is a G protein-coupled receptor-triggered signaling cascade used in cell communication. G protein-coupled receptors Adenylyl cyclase (ADCY, EC number 4.6.1.1), also known as adenylate cyclase, is an enzyme which catalyzes the cyclization of adenosine triphosphate (ATP) into cyclic adenosine monophosphate (cAMP). Catabolite gene activator protein CAMP-dependent protein kinase CAMP-dependent protein kinase CAMP Dependent Protein Kinase, Catalytic Subunit Protein Kinase A

spinqualitylabelsall models Structure of dog adenylyl cyclase 5 (grey), rat adenylyl cyclase 2 (green), bovine guanine nucleotide-binding protein subunit α (pink) complex with ADP derivative (stick model), GDP derivative (stick model), methylpiperazinoforskolin, Ca+2, Mg+2 and Cl- ions (PDB code 3maa). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image