9bul

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The structure of NiaR from Thermotoga maritima bound to nicotinic acidThe structure of NiaR from Thermotoga maritima bound to nicotinic acid

Structural highlights

9bul is a 1 chain structure with sequence from Thermotoga maritima. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NIAR_THEMA Probably functions to regulate transcription of NAD metabolic genes. Binds to DNA upstream of the probable nadBII/nadA/nadC and niaRP operons in a nicotinic acid dependent fashion. Nicotinic acid may be a corepressor.

9bul, resolution 2.10Å

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OCA