9b8s

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Human polymerase epsilon bound to PCNA and DNA in the nucleotide exchange stateHuman polymerase epsilon bound to PCNA and DNA in the nucleotide exchange state

Structural highlights

9b8s is a 6 chain structure with sequence from DNA molecule and Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 5.01Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

DPOE1_HUMAN Facial dysmorphism - immunodeficiency - livedo - short stature. Disease susceptibility is associated with variations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.

Function

DPOE1_HUMAN Participates in DNA repair and in chromosomal DNA replication.

9b8s, resolution 5.01Å

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OCA