8z4f

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Pseudomurein Endoisopeptidases PeiPPseudomurein Endoisopeptidases PeiP

Structural highlights

8z4f is a 2 chain structure with sequence from Methanobacterium phage psiM2. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.88Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ENLYS_METM2 Cysteine protease that cleaves the cell wall of its host methanogen under hydrogen limitation of the latter (autolysis) (PubMed:11934493). Cleaves the epsilon-Ala-Lys isopeptide bond in the oligopeptides of pseudomurein (PubMed:11934493).[1]

References

  1. Luo Y, Pfister P, Leisinger T, Wasserfallen A. Pseudomurein endoisopeptidases PeiW and PeiP, two moderately related members of a novel family of proteases produced in Methanothermobacter strains. FEMS Microbiol Lett. 2002 Feb 19;208(1):47-51. PMID:11934493 doi:10.1111/j.1574-6968.2002.tb11059.x

8z4f, resolution 1.88Å

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OCA