Structural highlights
Function
ENLYS_METM2 Cysteine protease that cleaves the cell wall of its host methanogen under hydrogen limitation of the latter (autolysis) (PubMed:11934493). Cleaves the epsilon-Ala-Lys isopeptide bond in the oligopeptides of pseudomurein (PubMed:11934493).[1]
References
- ↑ Luo Y, Pfister P, Leisinger T, Wasserfallen A. Pseudomurein endoisopeptidases PeiW and PeiP, two moderately related members of a novel family of proteases produced in Methanothermobacter strains. FEMS Microbiol Lett. 2002 Feb 19;208(1):47-51. PMID:11934493 doi:10.1111/j.1574-6968.2002.tb11059.x