8xx7

Structure of CXCR2 bound to CXCL5 (CXCR2-CXCL5-Go Full map)Structure of CXCR2 bound to CXCL5 (CXCR2-CXCL5-Go Full map)

Structural highlights

8xx7 is a 10 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Electron Microscopy, Resolution 3.32Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CXCL5_HUMAN Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes.^[1]

References

↑ Wuyts A, Govaerts C, Struyf S, Lenaerts JP, Put W, Conings R, Proost P, Van Damme J. Isolation of the CXC chemokines ENA-78, GRO alpha and GRO gamma from tumor cells and leukocytes reveals NH2-terminal heterogeneity. Functional comparison of different natural isoforms. Eur J Biochem. 1999 Mar;260(2):421-9. PMID:10095777

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OCA

[1] Wuyts A, Govaerts C, Struyf S, Lenaerts JP, Put W, Conings R, Proost P, Van Damme J. Isolation of the CXC chemokines ENA-78, GRO alpha and GRO gamma from tumor cells and leukocytes reveals NH2-terminal heterogeneity. Functional comparison of different natural isoforms. Eur J Biochem. 1999 Mar;260(2):421-9. PMID:10095777

[1]

8xx7

Structure of CXCR2 bound to CXCL5 (CXCR2-CXCL5-Go Full map)Structure of CXCR2 bound to CXCL5 (CXCR2-CXCL5-Go Full map)

Structural highlights

Function

References

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8xx7

Structure of CXCR2 bound to CXCL5 (CXCR2-CXCL5-Go Full map)Structure of CXCR2 bound to CXCL5 (CXCR2-CXCL5-Go Full map)

Structural highlights

Function

References

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