8x0e

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Human FL Metabotropic glutamate receptor 5, mGlu5-5M with agonist and PAM, W785A mutantHuman FL Metabotropic glutamate receptor 5, mGlu5-5M with agonist and PAM, W785A mutant

Structural highlights

8x0e is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3.4Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GRM5_HUMAN Receptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current.

8x0e, resolution 3.40Å

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OCA