8wdc

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Structural organization of the palisade layer in intracellular mature vaccinia virionsStructural organization of the palisade layer in intracellular mature vaccinia virions

Structural highlights

8wdc is a 3 chain structure with sequence from Vaccinia virus WR. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 7.7Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PG136_VACCW Core protein 4a is the most abundant virion protein. Major component of the virion core that undergoes proteolytic processing during the immature virion (IV) to mature virion (MV) transition.[1]

References

  1. ↑ Heljasvaara R, Rodríguez D, Risco C, Carrascosa JL, Esteban M, Rodríguez JR. The major core protein P4a (A10L gene) of vaccinia virus is essential for correct assembly of viral DNA into the nucleoprotein complex to form immature viral particles. J Virol. 2001 Jul;75(13):5778-95. PMID:11390580 doi:10.1128/JVI.75.13.5778-5795.2001

8wdc, resolution 7.70Å

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OCA
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