8vhf

Cryo-EM structure of GPR119-Gs-Nb35 complex with small molecule agonist MBX-2982Cryo-EM structure of GPR119-Gs-Nb35 complex with small molecule agonist MBX-2982

Structural highlights 8vhf is a 5 chain structure with sequence from Escherichia coli, Homo sapiens, Lama glama and Oplophorus gracilirostris. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.51Å Ligands: Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function GBB1_HUMAN Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

spinqualitylabelsall models 8vhf, resolution 3.51Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image