8vca

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Crystal Structure of plant Carboxylesterase 15Crystal Structure of plant Carboxylesterase 15

Structural highlights

8vca is a 1 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CXE15_ARATH Binds to strigolactones (SLs) such as (-)-2'-epi-GR24(4DO), 5-deoxystrigol (5DS) and orobanchol, and catalyzes their hydrolysis; SL are phytohormones controlling shoot branching and communications between plants and microorganisms (PubMed:34764442). Promotes shoot branching by dampening SL-inhibited axillary bud outgrowth (PubMed:34764442).[1]

References

  1. Xu E, Chai L, Zhang S, Yu R, Zhang X, Xu C, Hu Y. Catabolism of strigolactones by a carboxylesterase. Nat Plants. 2021 Nov;7(11):1495-1504. PMID:34764442 doi:10.1038/s41477-021-01011-y

8vca, resolution 2.30Å

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OCA