8kd9

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Cryo-EM structure of Aquifex aeolicus minimal protein-only RNase P (HARP) in complex with pre-tRNAsCryo-EM structure of Aquifex aeolicus minimal protein-only RNase P (HARP) in complex with pre-tRNAs

Structural highlights

8kd9 is a 17 chain structure with sequence from Aquifex aeolicus VF5. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 2.87Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RFRNP_AQUAE RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.[HAMAP-Rule:MF_01078][1]

References

  1. Nickel AI, Waber NB, Gossringer M, Lechner M, Linne U, Toth U, Rossmanith W, Hartmann RK. Minimal and RNA-free RNase P in Aquifex aeolicus. Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11121-11126. doi:, 10.1073/pnas.1707862114. Epub 2017 Oct 3. PMID:29073018 doi:http://dx.doi.org/10.1073/pnas.1707862114

8kd9, resolution 2.87Å

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OCA