8k9c

Structure of human Caprin-2 HR1 domainStructure of human Caprin-2 HR1 domain

Structural highlights

8k9c is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.32Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CAPR2_HUMAN May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons. Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation. May be involved in apoptosis.^[1]

References

↑ Aerbajinai W, Lee YT, Wojda U, Barr VA, Miller JL. Cloning and characterization of a gene expressed during terminal differentiation that encodes a novel inhibitor of growth. J Biol Chem. 2004 Jan 16;279(3):1916-21. Epub 2003 Oct 30. PMID:14593112 doi:http://dx.doi.org/10.1074/jbc.M305634200

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OCA

[1] Aerbajinai W, Lee YT, Wojda U, Barr VA, Miller JL. Cloning and characterization of a gene expressed during terminal differentiation that encodes a novel inhibitor of growth. J Biol Chem. 2004 Jan 16;279(3):1916-21. Epub 2003 Oct 30. PMID:14593112 doi:http://dx.doi.org/10.1074/jbc.M305634200

[1]

8k9c

Structure of human Caprin-2 HR1 domainStructure of human Caprin-2 HR1 domain

Structural highlights

Function

References

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8k9c

Structure of human Caprin-2 HR1 domainStructure of human Caprin-2 HR1 domain

Structural highlights

Function

References

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