8k3d
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Crystal structure of NRF1 DBD bound to DNACrystal structure of NRF1 DBD bound to DNA
Structural highlights
FunctionNRF1_HUMAN Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. |
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