8jg4

Crystal Structure of YAF9A YEATS bound to H3K27cr peptideCrystal Structure of YAF9A YEATS bound to H3K27cr peptide

Structural highlights

8jg4 is a 4 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.3Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TA14B_ARATH Negative regulator of flowering controlling the H4K5 acetylation levels in the FLC and FT chromatin. Positively regulates FLC expression. Component of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of a NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A.^[1] [REFERENCE:9]

References

↑ Zacharaki V, Benhamed M, Poulios S, Latrasse D, Papoutsoglou P, Delarue M, Vlachonasios KE. The Arabidopsis ortholog of the YEATS domain containing protein YAF9a regulates flowering by controlling H4 acetylation levels at the FLC locus. Plant Sci. 2012 Nov;196:44-52. PMID:23017898 doi:10.1016/j.plantsci.2012.07.010

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OCA

[1] Zacharaki V, Benhamed M, Poulios S, Latrasse D, Papoutsoglou P, Delarue M, Vlachonasios KE. The Arabidopsis ortholog of the YEATS domain containing protein YAF9a regulates flowering by controlling H4 acetylation levels at the FLC locus. Plant Sci. 2012 Nov;196:44-52. PMID:23017898 doi:10.1016/j.plantsci.2012.07.010

[1]

8jg4

Crystal Structure of YAF9A YEATS bound to H3K27cr peptideCrystal Structure of YAF9A YEATS bound to H3K27cr peptide

Structural highlights

Function

References

Contents

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8jg4

Crystal Structure of YAF9A YEATS bound to H3K27cr peptideCrystal Structure of YAF9A YEATS bound to H3K27cr peptide

Structural highlights

Function

References

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