8g01

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YES Complex - E. coli MraY, Protein E ID21, E. coli SlyDYES Complex - E. coli MraY, Protein E ID21, E. coli SlyD

Structural highlights

8g01 is a 6 chain structure with sequence from Escherichia coli K-12 and Escherichia phage ID21. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3.4Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MRAY_ECOLI Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.[HAMAP-Rule:MF_00038][1] [2]

See Also

References

  1. Ikeda M, Wachi M, Jung HK, Ishino F, Matsuhashi M. The Escherichia coli mraY gene encoding UDP-N-acetylmuramoyl-pentapeptide: undecaprenyl-phosphate phospho-N-acetylmuramoyl-pentapeptide transferase. J Bacteriol. 1991 Feb;173(3):1021-6. PMID:1846850 doi:10.1128/jb.173.3.1021-1026.1991
  2. Geis A, Plapp R. Phospho-N-acetylmuramoyl-pentapeptide-transferase of Escherichia coli K12. Properties of the membrane-bound and the extracted and partially purified enzyme. Biochim Biophys Acta. 1978 Dec 8;527(2):414-24. PMID:215212 doi:10.1016/0005-2744(78)90355-8

8g01, resolution 3.40Å

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OCA