8ej3

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M. tuberculosis RNAP pause escaped complex with Bacillus subtilis NusG and GMPCPPM. tuberculosis RNAP pause escaped complex with Bacillus subtilis NusG and GMPCPP

Structural highlights

8ej3 is a 9 chain structure with sequence from Bacillus subtilis subsp. subtilis str. 168, Mycobacterium tuberculosis H37Rv, Synthetic RNA and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3.13Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RPOA_MYCTU DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_00059][1]

See Also

References

  1. Hu Y, Morichaud Z, Chen S, Leonetti JP, Brodolin K. Mycobacterium tuberculosis RbpA protein is a new type of transcriptional activator that stabilizes the sigma A-containing RNA polymerase holoenzyme. Nucleic Acids Res. 2012 Aug;40(14):6547-57. doi: 10.1093/nar/gks346. Epub 2012, May 8. PMID:22570422 doi:http://dx.doi.org/10.1093/nar/gks346

8ej3, resolution 3.13Å

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OCA