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CryoEM structure of miniGo-coupled hM4Di in complex with DCZCryoEM structure of miniGo-coupled hM4Di in complex with DCZ
Structural highlights
FunctionACM4_HUMAN The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase. |
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