8e14

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Cryo-EM structure of Rous sarcoma virus strand transfer complexCryo-EM structure of Rous sarcoma virus strand transfer complex

Structural highlights

8e14 is a 14 chain structure with sequence from Rous sarcoma virus (strain Schmidt-Ruppin A). Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3.36Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

POL_RSVP Capsid protein p27 forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell (By similarity).

See Also

8e14, resolution 3.36Å

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OCA