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Heterogeneous nuclear ribonucleoprotein H1, qRRM2 domainHeterogeneous nuclear ribonucleoprotein H1, qRRM2 domain
Structural highlights
DiseaseHNRH1_HUMAN Precursor T-cell acute lymphoblastic leukemia. FunctionHNRH1_HUMAN This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG).[1] [2] See AlsoReferences
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