7ypi

Spiral hexamer of the substrate-free Lon protease with a Y224S mutationSpiral hexamer of the substrate-free Lon protease with a Y224S mutation

Structural highlights

7ypi is a 6 chain structure with sequence from Meiothermus taiwanensis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Electron Microscopy, Resolution 3.8Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

A0A059VAZ3_9DEIN ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.[HAMAP-Rule:MF_01973]

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7ypi

Spiral hexamer of the substrate-free Lon protease with a Y224S mutationSpiral hexamer of the substrate-free Lon protease with a Y224S mutation

Structural highlights

Function

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7ypi

Spiral hexamer of the substrate-free Lon protease with a Y224S mutationSpiral hexamer of the substrate-free Lon protease with a Y224S mutation

Structural highlights

Function

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