7yl9

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Cryo-EM structure of complete transmembrane channel E289A mutant Vibrio cholerae CytolysinCryo-EM structure of complete transmembrane channel E289A mutant Vibrio cholerae Cytolysin

Structural highlights

7yl9 is a 7 chain structure with sequence from Vibrio cholerae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 4.7Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HLYA_VIBCH Bacterial hemolysin that causes cytolysis by forming heptameric pores in target host membranes.[1]

See Also

References

  1. Olson R, Gouaux E. Crystal structure of the Vibrio cholerae cytolysin (VCC) pro-toxin and its assembly into a heptameric transmembrane pore. J Mol Biol. 2005 Jul 29;350(5):997-1016. PMID:15978620 doi:10.1016/j.jmb.2005.05.045

7yl9, resolution 4.70Å

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OCA