7tug

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Crystal structure of Tapasin in complex with PaSta2-FabCrystal structure of Tapasin in complex with PaSta2-Fab

Structural highlights

7tug is a 3 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.9Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TPSN_HUMAN Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).[1]

See Also

References

  1. Li S, Paulsson KM, Chen S, Sjogren HO, Wang P. Tapasin is required for efficient peptide binding to transporter associated with antigen processing. J Biol Chem. 2000 Jan 21;275(3):1581-6. PMID:10636848

7tug, resolution 3.90Å

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OCA