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Crystal structure of a peptide chain release factor 3 (prfC) from Stenotrophomonas maltophilia bound to GDPCrystal structure of a peptide chain release factor 3 (prfC) from Stenotrophomonas maltophilia bound to GDP
Structural highlights
FunctionRF3_STRMK Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.[HAMAP-Rule:MF_00072] |
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