7qu4

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Recombinant Human Fetal Hemoglobin mutant - alpha subunit mutations K11E,K56E,N78D,K90ERecombinant Human Fetal Hemoglobin mutant - alpha subunit mutations K11E,K56E,N78D,K90E

Structural highlights

7qu4 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.66Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

HBG2_HUMAN Hereditary persistence of fetal hemoglobin - beta-thalassemia;Hereditary persistence of fetal hemoglobin - sickle cell disease;Hemoglobinopathy Toms River. The disease is caused by mutations affecting the gene represented in this entry.

Function

HBG2_HUMAN Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.

See Also

7qu4, resolution 1.66Å

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OCA