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Nuclear factor one X - NFIX in P21Nuclear factor one X - NFIX in P21
Structural highlights
DiseaseNFIX_HUMAN Marshall-Smith syndrome;Malan overgrowth syndrome;19p13.3 microduplication syndrome. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. FunctionNFIX_HUMAN Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. |
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