7a3k

Crystal structure of DPP8 in complex with a b-lactam based inhibitor, A296.1Crystal structure of DPP8 in complex with a b-lactam based inhibitor, A296.1

Structural highlights

7a3k is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.65Å
Ligands:	, , ,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DPP8_HUMAN Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. May play a role in T-cell activation and immune function.^[1]

References

↑ Abbott CA, Yu DM, Woollatt E, Sutherland GR, McCaughan GW, Gorrell MD. Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8. Eur J Biochem. 2000 Oct;267(20):6140-50. PMID:11012666

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OCA

[1] Abbott CA, Yu DM, Woollatt E, Sutherland GR, McCaughan GW, Gorrell MD. Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8. Eur J Biochem. 2000 Oct;267(20):6140-50. PMID:11012666

[1]

7a3k

Crystal structure of DPP8 in complex with a b-lactam based inhibitor, A296.1Crystal structure of DPP8 in complex with a b-lactam based inhibitor, A296.1

Structural highlights

Function

See Also

References

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7a3k

Crystal structure of DPP8 in complex with a b-lactam based inhibitor, A296.1Crystal structure of DPP8 in complex with a b-lactam based inhibitor, A296.1

Structural highlights

Function

See Also

References

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