6x7a

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Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor SGT572Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor SGT572

Structural highlights

6x7a is a 1 chain structure with sequence from Mycobacterium tuberculosis H37Rv. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.08Å
Ligands:, , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

EIS_MYCTU May participate in pathogenesis, possibly by enhancing survival of the bacteria in host macrophages during infection.[1]

References

  1. ↑ Wei J, Dahl JL, Moulder JW, Roberts EA, O'Gaora P, Young DB, Friedman RL. Identification of a Mycobacterium tuberculosis gene that enhances mycobacterial survival in macrophages. J Bacteriol. 2000 Jan;182(2):377-84. PMID:10629183

6x7a, resolution 2.08Å

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OCA
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