6vnp

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Crystal structure of DPO4 extension past 8-oxoadenine (oxoA) and dTCrystal structure of DPO4 extension past 8-oxoadenine (oxoA) and dT

Structural highlights

6vnp is a 12 chain structure with sequence from Homo sapiens and Saccharolobus solfataricus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.42Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DPO4_SACS2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. It is involved in translesional synthesis.

See Also

6vnp, resolution 2.42Å

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OCA