6txq

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The high resolution structure of the FERM domain and helical linker of human moesinThe high resolution structure of the FERM domain and helical linker of human moesin

Structural highlights

6txq is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.73Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MOES_HUMAN Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage.[1]

See Also

References

  1. ↑ Henning MS, Stiedl P, Barry DS, McMahon R, Morham SG, Walsh D, Naghavi MH. PDZD8 is a novel moesin-interacting cytoskeletal regulatory protein that suppresses infection by herpes simplex virus type 1. Virology. 2011 Jul 5;415(2):114-21. doi: 10.1016/j.virol.2011.04.006. Epub 2011, May 6. PMID:21549406 doi:10.1016/j.virol.2011.04.006

6txq, resolution 1.73Å

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OCA
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