6pvs

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Structure of Nicotinamide N-Methyltransferase (NNMT) in complex with inhibitor LL320Structure of Nicotinamide N-Methyltransferase (NNMT) in complex with inhibitor LL320

Structural highlights

6pvs is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.575Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NNMT_HUMAN Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds.

6pvs, resolution 2.58Å

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OCA