6l90

Crystal structure of ugt transferase enzymeCrystal structure of ugt transferase enzyme

Structural highlights

6l90 is a 1 chain structure with sequence from Siraitia grosvenorii. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.02Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

74AC1_SIRGR Catalyzes the transfer of a glucose moiety to the C-3 hydroxyl of mogrol to form mogroside IE (PubMed:25759326, Ref.3). Besides mogrol, UGT74AC1 also shows activity in vitro with quercetin and naringenin as substrate (PubMed:25759326).^[1] ^[2]

References

↑ Dai L, Liu C, Zhu Y, Zhang J, Men Y, Zeng Y, Sun Y. Functional Characterization of Cucurbitadienol Synthase and Triterpene Glycosyltransferase Involved in Biosynthesis of Mogrosides from Siraitia grosvenorii. Plant Cell Physiol. 2015 Jun;56(6):1172-82. PMID:25759326 doi:10.1093/pcp/pcv043
↑ Dai L, Liu C, Zhu Y, Zhang J, Men Y, Zeng Y, Sun Y. Functional Characterization of Cucurbitadienol Synthase and Triterpene Glycosyltransferase Involved in Biosynthesis of Mogrosides from Siraitia grosvenorii. Plant Cell Physiol. 2015 Jun;56(6):1172-82. PMID:25759326 doi:10.1093/pcp/pcv043

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OCA

[1] Dai L, Liu C, Zhu Y, Zhang J, Men Y, Zeng Y, Sun Y. Functional Characterization of Cucurbitadienol Synthase and Triterpene Glycosyltransferase Involved in Biosynthesis of Mogrosides from Siraitia grosvenorii. Plant Cell Physiol. 2015 Jun;56(6):1172-82. PMID:25759326 doi:10.1093/pcp/pcv043

[2] Dai L, Liu C, Zhu Y, Zhang J, Men Y, Zeng Y, Sun Y. Functional Characterization of Cucurbitadienol Synthase and Triterpene Glycosyltransferase Involved in Biosynthesis of Mogrosides from Siraitia grosvenorii. Plant Cell Physiol. 2015 Jun;56(6):1172-82. PMID:25759326 doi:10.1093/pcp/pcv043

[1]

[2]

6l90

Crystal structure of ugt transferase enzymeCrystal structure of ugt transferase enzyme

Structural highlights

Function

See Also

References

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6l90

Crystal structure of ugt transferase enzymeCrystal structure of ugt transferase enzyme

Structural highlights

Function

See Also

References

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