6ksb

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Crystal Structure of E447A M130G Acyl-CoA Dehydrogenase FadE5 mutant from Mycobacteria smegmatis in complex with C16CoACrystal Structure of E447A M130G Acyl-CoA Dehydrogenase FadE5 mutant from Mycobacteria smegmatis in complex with C16CoA

Structural highlights

6ksb is a 2 chain structure with sequence from Mycolicibacterium smegmatis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.973Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FADE5_MYCS2 Acyl-CoA dehydrogenase that exhibits broad specificity for linear acyl-CoA substrates, with a preference for long-chain substrates.[1]

See Also

References

  1. ↑ Chen X, Chen J, Yan B, Zhang W, Guddat LW, Liu X, Rao Z. Structural basis for the broad substrate specificity of two acyl-CoA dehydrogenases FadE5 from mycobacteria. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16324-16332. PMID:32601219 doi:10.1073/pnas.2002835117

6ksb, resolution 1.97Å

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OCA
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