6jde

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crystal structure of a DNA repair proteincrystal structure of a DNA repair protein

Structural highlights

6jde is a 2 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.8Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RADD_ECOLI May be a helicase. In combination with RadA is important in repair of double-strand DNA breaks (DSB) (PubMed:25425430, PubMed:25484163).[1] [2]

References

  1. Chen SH, Byrne RT, Wood EA, Cox MM. Escherichia coli radD (yejH) gene: a novel function involved in radiation resistance and double-strand break repair. Mol Microbiol. 2015 Mar;95(5):754-68. doi: 10.1111/mmi.12885. Epub 2015 Jan 16. PMID:25425430 doi:http://dx.doi.org/10.1111/mmi.12885
  2. Cooper DL, Boyle DC, Lovett ST. Genetic analysis of Escherichia coli RadA: functional motifs and genetic interactions. Mol Microbiol. 2015 Mar;95(5):769-79. doi: 10.1111/mmi.12899. Epub 2015 Jan 30. PMID:25484163 doi:http://dx.doi.org/10.1111/mmi.12899

6jde, resolution 2.80Å

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OCA