6aw7

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2.15A resolution structure of SAH bound catechol O-methyltransferase (COMT) from Nannospalax galili2.15A resolution structure of SAH bound catechol O-methyltransferase (COMT) from Nannospalax galili

Structural highlights

6aw7 is a 2 chain structure with sequence from Nannospalax galili. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.15Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

A0A452CSQ0_NANGA Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.[ARBA:ARBA00003256]

See Also

6aw7, resolution 2.15Å

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OCA