6ago

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Crystal structure of MRG15-ASH1L Histone methyltransferase complexCrystal structure of MRG15-ASH1L Histone methyltransferase complex

Structural highlights

6ago is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.103Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ASH1L_HUMAN Histone methyltransferase specifically methylating 'Lys-36' of histone H3 (H3K36me).[1]

See Also

References

  1. ↑ An S, Yeo KJ, Jeon YH, Song JJ. Crystal structure of the human histone methyltransferase ASH1L catalytic domain and its implications for the regulatory mechanism. J Biol Chem. 2011 Mar 11;286(10):8369-74. Epub 2011 Jan 14. PMID:21239497 doi:10.1074/jbc.M110.203380

6ago, resolution 3.10Å

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OCA
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