5ymr

The Crystal Structure of IseGThe Crystal Structure of IseG

Structural highlights

5ymr is a 4 chain structure with sequence from Desulfovibrio vulgaris str. Hildenborough. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.4Å
Ligands:	,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ISLA_DESVH Involved in an anaerobic respiration pathway that converts the sulfonate isethionate (2-hydroxyethanesulfonate) to ammonia, acetate and sulfide. Catalyzes the radical-mediated C-S bond cleavage of isethionate (2-hydroxyethanesulfonate) to form sulfite and acetaldehyde. Shows no activity with taurine or ethanolamine as substrates.^[1]

References

↑ Xing M, Wei Y, Zhou Y, Zhang J, Lin L, Hu Y, Hua G, N Nanjaraj Urs A, Liu D, Wang F, Guo C, Tong Y, Li M, Liu Y, Ang EL, Zhao H, Yuchi Z, Zhang Y. Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria. Nat Commun. 2019 Apr 8;10(1):1609. doi: 10.1038/s41467-019-09618-8. PMID:30962433 doi:http://dx.doi.org/10.1038/s41467-019-09618-8

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OCA

[1] Xing M, Wei Y, Zhou Y, Zhang J, Lin L, Hu Y, Hua G, N Nanjaraj Urs A, Liu D, Wang F, Guo C, Tong Y, Li M, Liu Y, Ang EL, Zhao H, Yuchi Z, Zhang Y. Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria. Nat Commun. 2019 Apr 8;10(1):1609. doi: 10.1038/s41467-019-09618-8. PMID:30962433 doi:http://dx.doi.org/10.1038/s41467-019-09618-8

[1]

5ymr

The Crystal Structure of IseGThe Crystal Structure of IseG

Structural highlights

Function

References

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5ymr

The Crystal Structure of IseGThe Crystal Structure of IseG

Structural highlights

Function

References

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