5t2q

Unliganded Human HVEM at 1.9A in P 1 21 1Unliganded Human HVEM at 1.9A in P 1 21 1

Structural highlights

5t2q is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.9Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TNR14_HUMAN Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.^[1]

References

↑ Montgomery RI, Warner MS, Lum BJ, Spear PG. Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family. Cell. 1996 Nov 1;87(3):427-36. PMID:8898196

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OCA

[1] Montgomery RI, Warner MS, Lum BJ, Spear PG. Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family. Cell. 1996 Nov 1;87(3):427-36. PMID:8898196

[1]

5t2q

Unliganded Human HVEM at 1.9A in P 1 21 1Unliganded Human HVEM at 1.9A in P 1 21 1

Structural highlights

Function

See Also

References

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5t2q

Unliganded Human HVEM at 1.9A in P 1 21 1Unliganded Human HVEM at 1.9A in P 1 21 1

Structural highlights

Function

See Also

References

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